1. They think entrepreneurship is only about starting a business. 2. They are afraid of what they don't understand. 3. The culture discourages adopting an entrepreneurial mindset. 4. They think money is dirty in medicine. 5. They think it erodes medical professionalism. 6. They are just too busy. 7. They have had a bad experience before or working with "business people." 8. They actually believe doctors are bad business people. 9. They assume the costs exceed the benefits. 10. They are satisfied with what they are doing now and think switching to something else is too risky, particularly when they are, on average, $170,000 in debt when they graduate medical school. Source