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Anti-oncogenes

Discussion in 'Oncology' started by Ajhasan, Jan 5, 2014.

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What was the 1st dicovered anti-oncogene??

Poll closed Jan 12, 2014.
  1. RB

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  2. P53

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  1. Ajhasan

    Ajhasan Active member

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    Anti-oncogenes or tumor suppressor genes are believed to suppress the neoplasia progression .
    The 1st anti-oncogene was found in the (retinoblastoma) it's located on the chromosome number 13 and called RB .
    The familial form of this tumor appears as an autosomal dominant gene , in affected children we find one gene(muted) and another (normal).
    The progression of retinoblastoma must be associated with another somatic mutation in the affected child.
    We found that this anti-oncogene is upsent in the Retinoblastoma and also in many other tumors..
     

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