A 5 year old orphan child presented with pharyngitis,cold,with cervical lymphadenopathy.On abdominal examination he was found to have hepatosplenomegaly.His vaccination history is not clear but has a history of 1 unit blood transfusion after a car accident 3 months ago. Initially infectious mononucleosis is suspected and his blood is sent to the lab. Report suggests atypical lymphocytes but negative heterophile antibodies. His lymph nodes are taken for biopsy and they show a cytoplasmic inclusion body with a typical owl's eye appearance. What is your diagnosis? How will you manage the patient?(Y)(Y)
well,cytoplasmic inclusion bodies and a mononucleosis like presentation with atypical lymphocytes and heterophile negative antibodies suggest toxoplasmosis or CMV as the most common causative organisms...since he has history of blood transfusion a yr back...CMV infection seems mist likely.
