Comparing Respiratory Syncytial Virus And Rhinovirus In Development Of Post- Viral Airway Disease

The present study was carried out to compare respiratory syncytial virus and rhinovirus in development of post-viral airway disease. Researchers used peer-reviewed manuscripts listed in PubMed that had relevance to respiratory syncytial virus (RSV)/ rhinovirus (RV) and development of atopic/airway disease in both humans and mice. They selected studies that explained the mechanisms behind antiviral response. It was shown that both RSV and RV are correlated with a risk for developing post-viral airway disease and atopy. Nevertheless, the mechanisms that connect these viruses with post-viral disease seem to be different, implying that treatments to prevent post-viral airway disease may need to be specific to the viral etiology. RSV infections were linked with post-viral airway disease primarily in those without preexisting atopy; RV infection also can drive post-viral airway disease, but unlike RSV, this seems to happen only in those with preexisting atopy. ,

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