Correct answer: Osler nodes. These are painful lesions that can form on the hands or feet, caused by deposition of immune complexes. It's most often seen in infective endocarditis, although it can also occur in SLE.
As far as i know that the only difference in distinguishing the two lesions clinically in IE is whether it is painful or not.......If painful then osler nosdes and if Painless then Janeway lesion......
According to the Oxford Handbook of Clinical Medicine (8th edition), Osler nodes are the painful lesions and Janeway lesions the painless ones. It's also on Wikipedia by the way, I checked that as well.