Female Hormone Estrogen May Not Be Only Cause Of Endometriosis: Study

Endometriosis is a painful condition, in which a tissue that normally grows in the uterus, grow outside it, often in the ovaries and fallopian tubes.

“These studies were based on the rationale that as estrogen allows the growth of the normal tissue in the uterus, it must also promote growth of tissue outside as well. So we decided to check if estrogen was actually responsible for growth of uterine tissues in ovaries and fallopian tubes,” said Dr Modi

By studying mice, the scientists found that although estrogen allowed the endometrial tissue to stay for more number of days than the control group, they did not grow. Instead, they started dying even with excess of estrogen said Dr Modi.

“This meant that the other causative factors required for the development of the endometriosis,” he added. The study was published in Journal of Biosciences on May 11 2017.

The study finds importance as most treatments available for endometriosis today are ‘anti-estrogen’ therapies, which don’t work in most cases, according to doctors.

“Our results explain why anti-estrogen therapy doesn’t work and we need to search for newer treatment modalities for endometriosis,” said Modi.




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