If you struggle, it could be an early sign of dementia, scientists claim A delayed brain response to processing words may be an early sign of dementia The findings could pave the way for a reading test to identify people at great risk Brain scans showed that slower responses are 'aberrant' in individuals who will go onto develop Alzheimer's disease If you often find yourself struggling to read simple words, it could be an early sign of dementia. A delayed brain response to processing words may flag up individuals vulnerable to the neurological disease before symptoms even begin, scientists claim. Researchers hope the findings will pave the way for a simple reading test to identify people at great risk of developing Alzheimer's disease. This would allow an earlier diagnosis of the disease, a goal dedicated scientists have attempted to reach for years, albeit unsuccessfully. The study, led by experts at the University of Birmingham, offer hope of potentially finding a cure for dementia in the coming years. A delayed brain response to processing words may flag up individuals vulnerable to the neurological disease before symptoms even begin, scientists claim Some 25 participants took part in the trial, which saw them have to read a written word related to a phrase they heard moments before. Brain scans showed that slower responses are 'aberrant' in individuals who will go onto develop Alzheimer's disease, the study published in Neuroimage Clinical found. Dr Katrien Segaert, lead author, said: 'Our findings were unexpected as language is usually affected by Alzheimer's in much later stages of the onset of the disease. 'It is possible this breakdown of the brain network associated with language... could be a crucial biomarker used to identify patients likely to develop Alzheimer's.' How was the study carried out? Participants were healthy elderly people, along with mild cognitive impairment (MCI) patients. They were fitted with EEG (electroencephalogram) skull caps. Detecting electrical activity in the brain allows researchers to establish how quickly they processed words shown to them on a computer screen. Previous research has found that when a person is shown a written word, it takes 250 milliseconds for the brain to process it - activity which can be picked up on an EEG. What do the experts say? Dr Hilda Hayo, chief executive of Dementia UK, said the charity 'welcomes anything that can speed up the process of getting a diagnosis of dementia'. Clare Walton, research manager at Alzheimer’s Society, said 'research like this give us hope' of finding a way to diagnose the disease early on. However, she warned that it was too early to draw any firm conclusions and that larger studies are obviously needed to confirm the theory. MCI is estimated to be suffered by up to 20 per cent of people aged over 65. It is not a type of dementia, but a person with MCI is more likely to go on to develop it. Dementia: The facts Officials estimate there to be around 47 million dementia sufferers across the world, with nearly 10 million new cases reported each year. In the US, the devastating disease, which is currently incurable, affects more than five million, while 850,000 suffer in the UK. Diagnosing the disease earlier would offer hope of prescribing drugs when they are more likely to work, and encouraging lifestyle changes that can stave off dementia. One reason medications have so often failed in trials is they are given to patients when the devastating neurological illness has already taken hold. TAKE THE TEST TO DETERMINE YOUR RISK OF ALZHEIMER'S... The research, published in the journal Neuroimage Clinical, revolved around reading a phrase aloud to the 25 participants. Phrases used in the study included 'a type of wood' and 'a breakfast food' - all others have been devised by MailOnline. A second later, the volunteers were shown a word that was either congruent (oak, pancake), or just an every day noun. Those who took longer to recognise if the word was relevant to the phrase, measured by EEG tests, displayed early signs of cognitive impairment. It should be noted that the phrases created by MailOnline may not pose the same scientific accuracy as the ones devised by researchers. The first part of the test is also meant to be conducted aloud. Source
