Weight loss is almost always a result of healthy lifestyle changes and choices. Some weight loss is minor, such as a few pounds here or there. However, when someone is losing significant percentages of body weight, this is considered dramatic weight loss and other considerations will likely be made. For example, after you lose a significant amount of weight, you might find that you need help tightening the excess skin that results from the dramatic weight loss. 1- Perform exercises that tighten the areas of your body with loose skin as much as possible before undergoing medical procedures. Some common areas with loose skin after dramatic weight loss include the waist, stomach, upper back, thighs, knees, buttocks and arms. 2- Undergo laser treatments, as your skin recovers from the laser treatment, it will produce more collagen, which naturally tightens your skin. 3- Consider the possibility of body contouring. This is basically a type of plastic surgery that involves actually removing the excess skin along specific points. 4- Discuss the option of liposuction. Liposuction involves removing fat from beneath the skin to improve its appearance, and it often goes along with body contouring surgeries to help remove as much excess skin as possible. Source
According to me, losing a lot of weight at one time can be bad for you, not only with respect to your health, but in general too as it can make your skin sag. One of the best ways to tighten your skin after weight loss is to lose your weight gradually. Remember, time is your friend and your weight should be healthy. Exercise is the best way to tighten your skin rather than undergoing surgery.