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Organ Donor Had Kidney with Five Renal Arteries in Rare Medical Anomaly

Discussion in 'Organ transplantation' started by Hadeel Abdelkariem, Aug 31, 2019.

  1. Hadeel Abdelkariem

    Hadeel Abdelkariem Golden Member

    Apr 1, 2018
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    Doctors in the U.K. have announced a rare medical case where an organ donor's kidney was found to have five renal arteries. The kidney, which was about to be transplanted into a young girl, is extremely unusual. While it is not uncommon for people to have two renal arteries, more than three in a single organ is far less common.


    The kidney with five arteries. The organ was not transplanted into the nine-year-old girl because of the potential risks it posed.© THE NEW ENGLAND JOURNAL OF MEDICINE NEJM 2019

    Renal arteries supply blood to the kidneys. In the womb during fetal development, multiple proto arteries known as "mesonephric arteries" perform this task. In most cases only one artery persists, which then becomes the main source of blood.

    Having multiple renal arteries is common and often identified during transplant surgeries. The prevalence of multiple arteries varies, with one recent study finding an incident rate of between 17 and 35 percent. In a review paper looking at the outcome of multiple renal artery transplants, scientists found 12.8 percent of patients had kidneys with more than one artery.

    In the latest case report, doctors from Manchester said they were prepping the nine-year-old girl for surgery. She was suffering from chronic kidney disease and had a single dysplastic kidney—where the organ does not develop normally in the womb.
    "During preparation of the kidney for transplantation, the donor kidney was found to have five renal arteries," the team wrote in the NEJM.

    Transplanting a kidney with multiple arteries is riskier in children than it is adults, as it is more "technically challenging" and leads to an "increased risk of vascular complications," the team said. Because of this, the organ was given to a 35-year-old man instead of the girl. Three years later, the man was "clinically well."

    The girl eventually underwent a live donor kidney transplant and two years later she was also doing well.


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