Whether intralesional injection of vitamin D is an efficacious treatment strategy for keloids, both clinically and ultrasonically, was inquired in this study. Participants were 40 Egyptian patients with keloid scars. These were injected weekly with intralesional vitamin D with dose of 0.2 ml (200,000 IU) per 1 cm lesion. Following treatment with intralesional vitamin D injection, experts detected statistically highly significant decrease in Vancouver Scar Scale. Post-treatment, they also noted statistically highly significant improvement in ultrasonic keloid scar thickness. Overall, findings demonstrated effectiveness as well as safety of intralesional vitamin D in treating keloid scars. Experts suggested the usefulness of ultrasound as a tool for evaluating the improvement of keloids post-treatment. Source