A 30-year-old woman presents with fatigue, joint pain, and a malar rash. Bloods show Hb 9 g/dL, WBC 2.5, platelets 80, and positive anti-dsDNA. What is the most likely diagnosis? A) Rheumatoid arthritis B) systemic lupus erythematosus (SLE) C) Sjögren’s syndrome D) Scleroderma E) Vasculitis . Correct Answer: B) systemic lupus erythematosus (SLE) . Explanation: Malar rash + cytopenias + anti-dsDNA = SLE. ANA is also typically positive.
