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There May Be a Link Between Coffee and Lung Cancer, Study Suggests

Discussion in 'Oncology' started by Hadeel Abdelkariem, Apr 4, 2019.

  1. Hadeel Abdelkariem

    Hadeel Abdelkariem Golden Member

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    ATLANTA — Drinking coffee has been linked to a slew of health benefits, such as a longer life span, and a decreased risk of conditions including depression, heart attacks and certain cancers.

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    But a new study suggests that there may be a downside to your morning brew: Researchers found that drinking two or more cups of coffee or tea may increase a person's risk of lung cancer.

    The findings were presented on March 31, here at the annual meeting of the American Association for Cancer Research.

    Of note, the link was even true for nonsmokers. Because people who smoke cigarettes are also more likely to drink coffee and tea, it was difficult in previous studies to disentangle the effects of these drinks from those of smoking, in developing lung cancer, said lead study author Jingjing Zhu, a Ph.D. student at Vanderbilt University in Tennessee.

    In the new study, an international group of researchers analyzed data from 17 different studies that included a total of 1.2 million participants in the U.S. and Asia. The studies noted whether participants drank coffee or tea or smoked cigarettes. About half were nonsmokers.

    The participants were tracked for an average of 8.6 years. During that time, more than 20,500 participants developed lung cancer.

    The researchers found that nonsmokers who drank two or more cups of coffee a day had a 41 percent higher risk of lung cancer than those who didn't drink coffee. Similarly, nonsmokers who drank two or more cups of tea a day had a 37 percent greater risk of lung cancer than non-tea drinkers. (Because data was taken from multiple studies, the exact definition of a cup varied.)

    The study also found that a person's risk didn't change significantly between ages, races or the type of coffee people drank — both decaf and caffeinated coffee seemed to be associated with similar risks. In fact, decaf coffee was associated with a 15 percent higher risk than caffeinated coffee, Zhu said.

    Still, Zhu noted that "this [was] only an observational study" and didn't prove cause-and-effect. But the researchers hypothesize that it isn't caffeine that's behind the link. Instead, it may be that something in the roasting process is driving the link between coffee and lung cancer risk, Zhu told Live Science.

    The study had several limitations. For example, although the participants were tracked for years after the studies started, data on smoking and coffee and tea intake was measured only one time, at the beginning of the studies. So if people changed their behaviors throughout the years, it could have skewed the results, Zhu said.

    What's more, if nonsmokers were exposed to second-hand smoke — which wasn't accounted for but could also increase lung cancer risk — that could have also skewed the results, she said.

    Dr. Julie Fisher, an oncologist at the Levine Cancer Institute in North Carolina who was not part of the study, said that the findings were "interesting" and "compelling," but noted that because it's an association finding, she "certainly would not draw conclusions based on this."

    However, though there's still much more research needed, Fisher told Live Science that she agreed that "maybe there's something in the [coffee brewing] process" that's driving the link.

    Other coffee findings presented at the meeting were more comforting: Drinking coffee wasn't associated with an increased risk of glioma or colorectal cancer in men and women; nor was it associated with bladder cancer or renal cell carcinoma in male smokers. Coffee was found to be associated with a lower risk of breast cancer in post-menopausal women and tea with a lower risk of glioma in women. In both men and women, decaf coffee was found to be associated with a lower risk of colorectal cancer.

    The findings have not yet been published in a peer-reviewed journal.

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