Trends In Predominant Causes Of Death In Individuals With And Without Diabetes In England From 2001

This study was undertaken to calculate how all-cause mortality and cause-specific mortality in people with diabetes have changed over time, how the composition of the mortality burden has changed, and how this composition compared with that of the non-diabetes population. Researchers designed an epidemiological analysis of primary care records to distinguish 313,907 individuals with diabetes in the Clinical Practice Research Datalink, a well-described primary care database, between 2001 to 2018 and linked these data to UK Office for National Statistics mortality data. Serial cross-sections with longitudinal follow-up were assembled to generate a mixed prevalence and incidence study population of patients with diabetes. The results of this study exhibited that the decline in vascular death rates has been accompanied by a diversification of causes in individuals with diagnosed diabetes and a transition from vascular diseases to cancers as the leading contributor to diabetes-related death. In individuals with diabetes, clinical and preventative approaches must reflect this trend to decrease the excess mortality risk.

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