A small study links weighted-blanket use at bedtime to increased melatonin production. Using a weighted blanket at bedtime may boost the body's production of the sleep-promoting hormone melatonin, a small study suggests. However, at this point, it's unclear why the hefty blankets might increase melatonin levels and whether this significantly improves people's sleep quality, the study authors wrote in a report published Oct. 3 in the Journal of Sleep Research (opens in new tab). "This is a very interesting study, but it would be nice to see it replicated in a second cohort because it is not an obvious thing that melatonin should increase with a weighted blanket," Håkan Olausson (opens in new tab), a neuroscientist at Linköping University in Sweden, told The Washington Post (opens in new tab). Melatonin helps the body transition into sleep mode, during which body temperature falls, metabolism slows and levels of the stress hormone cortisol decrease; melatonin also increases drowsiness in the hours before bed. Melatonin levels generally increase in the evening, peak at night and decrease as morning approaches, according to BrainFacts.org (opens in new tab). That's because a part of the brain called the suprachiasmatic nucleus (SCN) syncs melatonin production with the time of day. The SCN does so by monitoring light-related signals from the retina. Bright light prompts the SCN to shoot electrical signals to other brain structures, which then relay the message through the spinal cord and on to organs. This chain message eventually reaches the pea-size pineal gland, which pauses its production of melatonin. Conversely, dim light and darkness lift the brakes on the pineal gland and jump-start melatonin production. In addition to light, environmental factors — such as the timing of meals, physical activity and social interactions — can sway somewhat when melatonin gets made, according to a 2005 review in the Journal of Biological Rhythms (opens in new tab). So scientists wondered whether a different sensory cue — the pressure of a weighted blanket — also might influence melatonin production. To investigate this question, they asked 11 women and 15 men in their 20s to spend a few nights sleeping in a lab — once to get used to the environment, once under a lightweight blanket and once under a weighted blanket. None of the study participants had insomnia or had previously used weighted blankets. During a session, each participant would eat dinner, sit in bright light for two hours and then sit in dim light until lights out at 11 p.m. One hour before lights out, they would snuggle up under either the lightweight blanket or the weighted blanket. In that hour, the researchers took saliva samples every 20 minutes to monitor each subject's melatonin levels. (Saliva melatonin concentrations are generally about 30% (opens in new tab) of what's present in a person's bloodstream.) On average, when under a weighted blanket, the participants' melatonin levels rose about 32% higher than they did under the lightweight blanket, although the study can't show why this was, the study authors noted. What's more, using the blanket did not seem to affect the participants' sleep; they were just as sleepy before bedtime and after waking up in both scenarios, and their total sleep time was the same in both scenarios. "Future studies should investigate whether the stimulatory effect on melatonin secretion is observed on a nightly basis when frequently using a weighted blanket over weeks to months," the study authors wrote. "It remains to be determined whether the observed increase in melatonin may be therapeutically relevant for the previously described effects of the weighted blanket on insomnia and anxiety." It's also not clear whether the observed melatonin boost would be seen in other groups, including older people, given that people's circadian rhythms often become disrupted with age, according to a 2019 review in the International Journal of Environmental Research and Public Health (opens in new tab). Source
