Malaria drug taken by Trump could raise risk of death and heart problems, study shows The World Health Organization has said it will temporarily drop hydroxychloroquine — the malaria drug Donald Trump said he is taking as a precaution — from its global study into experimental coronavirus treatments after safety concerns. The WHO’s director-general Tedros Adhanom Ghebreyesus said in light of a paper published last week in the Lancet that showed people taking hydroxychloroquine were at higher risk of death and heart problems than those who were not, it would pause the hydroxychloroquine arm of its solidarity global clinical trial. “The executive group has implemented a temporary pause of the hydroxychloroquine arm within the solidarity trial while the safety data is reviewed by the data safety monitoring board,” Tedros said on Monday. “The other arms of the trial are continuing,” He said the concern related only to the use of hydroxychloroquine and chloroquine for Covid-19, adding that the drugs were accepted treatments for people with malaria and auto-immune diseases. Other treatments in the WHO’s solidarity trial, including the experimental drug remdesivir and an HIV combination therapy, are still being pursued. Hydroxychloroquine has been licensed for use in the US since the mid-1950s and is listed by the WHO as an essential medicine. There are numerous trials under way of the two drugs against coronavirus but neither is a proven treatment. The US National Institutes of Health is also running a clinical trial to establish whether the drug, administered with the antibiotic azithromycin, can prevent hospital admissions and death from Covid-19. A controversial French doctor who has promoted the use of hydroxychloroquine and chloroquine for coronavirus said on Monday he stood by his belief the drugs could help patients recover. He also rejected the Lancet study of the records of 96,000 patients across hundreds of hospitals. “How can a messy study done with ‘big data’ change what we see?”, Prof Didier Raoult asked in a video posted on the website of his infectious diseases hospital in Marseille. “Here we have had 4,000 people go through our hospital, you don’t think I’m going to change because there are people who do ‘big data’, which is a kind of completely delusional fantasy,” he said. Source
