A 48-year old woman, who’s primary hypertension has been treated with a thiazide diuretic for 6 years, visits her family doctor because of pain in her right shoulder. Since her doctor thinks it’s periarthritis humeroscapularis, he prescribes fenoprofen (an NSAID). A few days later, she develops vague malaise-like symptoms and hits a temperature of 38,2Â° C. She thinks she’s having ”˜the flu’ and decides not to visit her doctor. However, one week later she does so anyway on the count of her urine turning dark and decreased diuresis. She also has edema around her ankles and her blood pressure is 160/100 mm Hg. The albustix result is positive (indicating albumin in the urine) and the sediment analysis reveals 20-25 erythrocytes and 15-20 leukocytes per high-power field. There are also eosinophils visible. Furthermore, her serum creatinine ”“ which was 95 micromol/l a year before ”“ is now 340 micromol/l and her serum albumin is 26 g/l. Questions. 1. What kidney disorder are we most likely dealing with? 2. Is this condition a result of the diuretic or of fenoprofen? 3. What investigations should be done? 4. What therapeutic measures do you have in mind?