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Apple Founder Steve Jobs’ Pancreatic Cancer

Discussion in 'Gastroenterology' started by Dr.Night, Jan 4, 2012.

  1. Dr.Night

    Dr.Night Famous Member

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    In October 2011, Apple founder Steve Jobs died at age 56 after a seven-year battle with pancreatic cancer, and as a result, patients are asking me about this disease. Jobs announced he had pancreatic cancer in 2004, battled the disease for years, and resigned as CEO of Apple in August 2011. Actor Patrick Swayze died from pancreatic cancer in September 2009. While pancreatic cancer is not one of the most common forms of cancer, it can be considered one of the most deadly because it is aggressive, spreads rapidly and thus often not diagnosed until it is in later stages, and few treatment options exist.


    The most common type of pancreatic cancer arises from the exocrine glands and is called adenocarcinoma of the pancreas. The endocrine glands of the pancreas can give rise to a completely different type of cancer, referred to as pancreatic neuroendocrine carcinoma or islet cell tumor.
    About 95% of exocrine pancreatic cancers are adenocarcinomas. While the pancreatic endocrine tumors, which make up about 1% of total cases. the remaining 5% include: acinar cell carcinomas, adenosquamous carcinomas, and undifferentiated carcinomas with osteoclast-like giant cells.This article only discusses issues
    related to the more common type of pancreatic adenocarcinoma.




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    Pancreatic Cancer Causes

    The main recognized risk factors for pancreatic cancer include the following:
    ӢSmoking
    ӢAdvanced age
    ”¢Male sex ”“ The male-to-female ratio of pancreatic cancer is 1.3:1.
    ”¢Chronic pancreatitis ”“ Inflammation of the pancreas, usually from excessive alcohol intake or gallstones
    ӢDiabetes mellitus
    ӢFamily history of pancreatic cancer
    Pancreatic Cancer Symptoms and Signs
    The main symptoms of pancreatic cancer include the following:
    ӢPain in the abdomen, the back, or both
    ӢWeight loss, often associated with the following:
    ◦Loss of appetite (anorexia)
    ◦Bloating
    ◦Diarrhea or fatty bowel movements that float in water (steatorrhea)
    ◦Rarely may present with new diabetes in a person with weight loss and nausea
    ӢJaundice (yellowing of the skin)
    The symptoms of pancreatic cancer are generally vague and can easily be attributed to other less serious and more common conditions. This lack of specific symptoms explains the high number of people who have a more advanced stage of disease when pancreatic cancer is discovered.


    Pancreatic Cancer Diagnosis

    ӢAbdominal ultrasound
    ӢAbdominal computed tomography (CT)
    ӢPercutaneous biopsy
    ӢEndoscopic biopsy
    In addition, a blood test called CA 19-9 is obtained. CA 19-9 is often produced by pancreatic cancers, and its level is elevated in 80% of pancreatic cancer cases. Checking the CA 19-9 levels can be a useful gauge of how the treatment is working. After treatment, the doctor may check the CA 19-9 levels regularly as one indicator of whether the cancer has returned. However, CA 19-9 is not an absolute test for pancreatic cancers, and other conditions may cause a rise in the CA 19-9 levels. Likewise, a normal CA 19-9 level is not a guarantee that the cancer has not returned.


    Pancreatic Cancer Treatment

    The optimal treatment of pancreatic adenocarcinoma depends on the extent of the disease. The extent of cancer can be divided into the following 3 categories:
    ӢLocalized: The cancer is completely confined within the pancreas.
    ӢLocally advanced: The cancer has extended from the pancreas to involve nearby blood vessels or organs.
    ӢMetastatic: The cancer has spread outside the pancreas to other parts of the body.

    Source : Apple Founder Steve Jobs
     

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  2. einfopedia

    einfopedia Well-Known Member

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    i was very sad when i listen about the steve.He underwent an operation for pancreatic cancer in 2004 and
    received a liver transplant two years ago.
    Steve was known as a visionary; in his private life, he cherished his family.
    We are thankful to the many people who have shared their wishes and prayers during the last year of Steve's illness;
    a link will be provided for those who wish to offer tributes and memories,"
     

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