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Discussion in 'Spot Diagnosis' started by Egyptian Doctor, Nov 23, 2012.

  1. Egyptian Doctor

    Egyptian Doctor Moderator Verified Doctor

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    What is your medical diagnosis ?

    Legs.jpg
     

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  2. neo_star

    neo_star Moderator

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    Osteogenesis Imperfecta
     

  3. dupuytren

    dupuytren Bronze Member

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    Arthrogryposis maybe
     

  4. dr.angela

    dr.angela Bronze Member

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    Osteogenesis imperfecta
     

  5. Emergency medicine Mike

    Emergency medicine Mike Bronze Member

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    Osteogenesis imperfecta.
     

  6. Rocket Queen

    Rocket Queen Super Moderator

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    Osteogenesis imperfecta
     

  7. drkdab

    drkdab Active member

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    osteogenesis imperfecta
     

  8. Gospodin Seki

    Gospodin Seki Moderator Staff Member

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    Osteogenesis Imperfecta
     

  9. summeragreen

    summeragreen Well-Known Member

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    Osteogenesis imperfecta makes sense
     

  10. Egyptian Doctor

    Egyptian Doctor Moderator Verified Doctor

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    Answer : Osteogenesis Imperfecta


     

  11. neo_star

    neo_star Moderator

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    Self Assessment Question

    [FONT=&quot]A 4-year-old child has blue sclera and a history of multiple fractures with minimal trauma. For this disorder, select the serum concentration of calcium (Ca2+) and phosphate (PO4) with which it is most likely to be associated.[/FONT]


    [FONT=&quot]A. Low PO4, normal Ca[/FONT]
    [FONT=&quot]B. Low PO4, high Ca[/FONT]
    [FONT=&quot]C. Normal PO4, low Ca[/FONT]
    [FONT=&quot]D. Normal PO4, normal Ca[/FONT]
    [FONT=&quot]E. High PO4, low Ca[/FONT]
    [FONT=&quot] [/FONT]
    [FONT=&quot]EXPLANATION: [/FONT]
    [FONT=&quot]Osteogenesis imperfecta (blue sclera, easily broken bones with minimal trauma) is transmitted as an autosomal recessive (severe form) or, more commonly, autosomal dominant (milder form) disorder. The basic defect is an abnormality in the production and composition of the matrix of bone. Serum calcium and phosphate concentrations are normal.

    [/FONT]

    [FONT=&quot]The answer is D.[/FONT]
     

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