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DDx

Discussion in 'Spot Diagnosis' started by J.P.C. Peper, Jun 16, 2012.

  1. J.P.C. Peper

    J.P.C. Peper Bronze Member

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    What's your diagnosis?

    I'll post the correct answer in about three days!

    DDx.jpg
     

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  2. Gospodin Seki

    Gospodin Seki Moderator Staff Member

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    Coumarine necrosis
     


  3. drabdallah_soliman

    drabdallah_soliman Well-Known Member

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    Big haematoma
     


  4. Zsana Gaál

    Zsana Gaál Well-Known Member

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    Warfarin Necrosis maybe...
     


  5. Rbrt

    Rbrt Well-Known Member

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    Coumarine induced skin necrosis
     


  6. Oxana

    Oxana Well-Known Member

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    coumarine necrosis of the mammary gland
     


  7. J.P.C. Peper

    J.P.C. Peper Bronze Member

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    Correct answer:

    Yes, it's warfarin induced skin necrosis.

    Clearly a serious complication of medication use; there is still debate about the disease mechanism (paradoxical activation of coagulation vs. direct toxic effect of warfarin vs. some kind of hypersensitivity reaction...).

    It usually occurs in obese, middle-aged women. When being confronted by this condition, you should also consider pyoderma gangrenosum and necrotizing fasciitis.
     


  8. Aman Setiya

    Aman Setiya Bronze Member

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    warfarin necrosis
     


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