What's your differential diagnosis, based on this CT-scan? I'll post the correct answer in a few days!
Correct answer: Yes, this is massive splenomegaly (>5 fingers) and the differential diagnosis (according to the Oxford Handbook of Clinical Diagnosis) is: - CML (check for the Philadelphia chromosome) - Myelofibrosis - Malaria - Visceral leishmaniasis (kala-azar) The differential diagnosis for moderate splenomegaly (3-5 fingers) (according to the Oxford Handbook of Clinical Diagnosis) is: - Lymphoma (Hodgkin's or non-Hodgkin's) - Chronic leukaemia - Cirrosis, with or without portal HT The differential diagnosis for slight splenomegaly (3> fingers) (according to the Oxford Handbook of Clinical Diagnosis) is: - Glandular fever - Brucella - Hepatitis A, B, C or D - Bacterial endocarditis - Amyloidosis - Hemolytic anaemia