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DDx

Discussion in 'Spot Diagnosis' started by J.P.C. Peper, Jul 27, 2012.

  1. J.P.C. Peper

    J.P.C. Peper Bronze Member

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    What's your differential diagnosis, based on this CT-scan?

    I'll post the correct answer in a few days!

    DDx.jpg
     

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  2. Sisca Dwi Agustina

    Sisca Dwi Agustina Active member

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  3. bb100

    bb100 Bronze Member

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    massive splenomegaly
     


  4. J.P.C. Peper

    J.P.C. Peper Bronze Member

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    Correct answer:

    Yes, this is massive splenomegaly (>5 fingers) and the differential diagnosis (according to the Oxford Handbook of Clinical Diagnosis) is:

    - CML (check for the Philadelphia chromosome)
    - Myelofibrosis
    - Malaria
    - Visceral leishmaniasis (kala-azar)

    The differential diagnosis for moderate splenomegaly (3-5 fingers) (according to the Oxford Handbook of Clinical Diagnosis) is:

    - Lymphoma (Hodgkin's or non-Hodgkin's)
    - Chronic leukaemia
    - Cirrosis, with or without portal HT

    The differential diagnosis for slight splenomegaly (3> fingers) (according to the Oxford Handbook of Clinical Diagnosis) is:

    - Glandular fever
    - Brucella
    - Hepatitis A, B, C or D
    - Bacterial endocarditis
    - Amyloidosis
    - Hemolytic anaemia
     

    Last edited: Jul 30, 2012

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