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DDx

Discussion in 'Spot Diagnosis' started by J.P.C. Peper, Aug 3, 2012.

  1. J.P.C. Peper

    J.P.C. Peper Bronze Member

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    What's your diagnosis, based on this bone marrow smear?

    It's a 4-year old patient with a fever, frequent sore throats and lethargy.

    I'll post the correct answer in about three days!

    DDx.jpg
     

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  2. dracomalfoy

    dracomalfoy Famous Member

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    Acute Lymphoblastic Leukemia
     


  3. J.P.C. Peper

    J.P.C. Peper Bronze Member

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    Correct answer:

    Yes, it's most likely to be ALL (probably subtype L2, because the blast cells are relatively large and have more abundant cytoplasm).

    ALL (acute lymphoblastic leukemia) is the commonest cancer of childhood, and rare in adults. Patients commonly present lethargic and show signs of aneamia, leukopenia (e.g. frequent sore throats) and trombopenia. Hepatosplenomegaly and lymphadenopathy are also frequently seen and indicate infiltration.
     


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