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DDx

Discussion in 'Spot Diagnosis' started by J.P.C. Peper, Aug 8, 2012.

  1. J.P.C. Peper

    J.P.C. Peper Bronze Member

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    This depicts two findings during progression of a disease.

    What's the most likely diagnosis?

    I'll post the correct answer in a couple of days!

    DDx.JPG
     

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    J.P.C. Peper, Aug 8, 2012
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  2. lakmalDJ

    lakmalDJ Famous Member

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    does this patient has a visual loss? probably Central retinal vein occlusion(CRVO)
     

    lakmalDJ, Aug 8, 2012
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  3. J.P.C. Peper

    J.P.C. Peper Bronze Member

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    Correct answer:

    This is DM retinopathy.

    Stage 1 shows pre-proliferative retinopathy, with hemorrhages and a cotton-wool spot. Stage 2 shows proliferative retinopathy, with new vessel formation and hemorrhages.

    Hyperglycemia induces a high retinal blood flow, which causes capillary occlusions (seen as cotton-wool spots). This then leeds to local hypoxia, ischemia and new vessel formation. These new vessels can bleed, fibrose and detach from the retina. Aspirin may prevent this.
     

    J.P.C. Peper, Aug 11, 2012
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