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DDx

Discussion in 'Spot Diagnosis' started by J.P.C. Peper, Aug 8, 2012.

  1. J.P.C. Peper

    J.P.C. Peper Bronze Member

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    This depicts two findings during progression of a disease.

    What's the most likely diagnosis?

    I'll post the correct answer in a couple of days!

    DDx.JPG
     

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  2. lakmalDJ

    lakmalDJ Famous Member

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    does this patient has a visual loss? probably Central retinal vein occlusion(CRVO)
     

  3. J.P.C. Peper

    J.P.C. Peper Bronze Member

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    Correct answer:

    This is DM retinopathy.

    Stage 1 shows pre-proliferative retinopathy, with hemorrhages and a cotton-wool spot. Stage 2 shows proliferative retinopathy, with new vessel formation and hemorrhages.

    Hyperglycemia induces a high retinal blood flow, which causes capillary occlusions (seen as cotton-wool spots). This then leeds to local hypoxia, ischemia and new vessel formation. These new vessels can bleed, fibrose and detach from the retina. Aspirin may prevent this.
     

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