What is the difference between connective tissue proper and cartilage tissue? The connective tissues proper is comprised of fibrocyte, ground substance of GAG, proteoglycan, glycoproteins, and primarily collagen fibers. Cartilages contain chondrocytes, which is a type of fibrocyte, and also includes GAG, proteoglycan, glycoproteins. And also of collegen fibers. What is the essential difference between them? I don’t understand And one off topic question. My husband was diagnosed with LBD in April. Because he is doing fine at the moment, we have opted to not go down the drug path at this stage. Does anyone have any experience with, or knowledge of, stem cell therapy and stem cell diseases as a treatment?