Melanocytic hamartomas ; Lisch nodules are the most common ocular manifestations in neurofibromatosis type 1. More than 95% of individuals with neurofibromatosis type 1 older than 10 years of age exhibit this finding. They consist of melanocytic hamartomas, which are usually brown or yellow in color and are evident as round elevations on the surface of the iris. They often are visible to the naked eye. However, optimal evaluation is with slit-lamp examination.