Discussion in 'Spot Diagnosis' started by bb100, Apr 18, 2013.
What is your medical diagnosis?
huge fleshy mass on tongue....can't be just plain macroglossia or hypthyroidism. Looks more like a tumor.
Congenital rhabdomyosarcoma of the tongue is exceedingly rare. Fibromatosis of the tongue is also rare, and very difficult to distinguish from the spindle cell variant of rhabdomyosarcoma. Both appear histologically as spindle neoplasms replacing normal striated musculature of the tongue. The treatment protocol for the former has been developed by the Intergroup Rhabdomyosarcoma Studies (IRS) I–IV and requires surgery, radiation, and chemotherapy. For fibromatosis, complete surgical excision is usually adequate without additional therapy, although some cases of aggressive fibromatosis also require chemotherapy. With significant differences in appropriate treatment and prognosis, each entity must not be mistaken for the other. We review the differences in radiologic, histologic, and immunohistochemical (IHC) features of both entities.
ref - http://www.sciencedirect.com/science/article/pii/S0165587610001722
Rhabdomyosarcoma most likely
I think so, imponate to rhabdomyosarcoma.
Correct diagnosis :
Enlarged protruding tongue- This may be associated with a tumor such as a teratoma or may occur as part of an organomegaly syndrome (Beckwith—Wiedemann). Beckwith—Wiedemann syndrome is associated with omphalocele, macroglossia gigantism, pancreatic hyperplasia . There is an increased incidence of Wilms’ tumors and hepatoblastomas.
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