Discussion in 'Spot Diagnosis' started by Egyptian Doctor, Nov 3, 2012.
What is your medical diagnosis for this case ?
Hypomelanosis of Ito
Answer : Mosaicam
Thanks Egyptian Doctor. Great post !
Hypomelanosis of Ito, i thought was a great guess by Chriss.
2 points that go against it though are
a) no hypomelamosis in the image - the area in between the hyperpigmented regions has the same skin color as the rest of the normal skin.
b) inspite of covering several dermatomes, it is strictly restricted to one half of the body
If these macule was on the dorsal surface and slightly more cohesive, i would have been tempted to go for Mongolian spots.
Thank you Egyptian Doctor and neo_star! I didn't know about the dermatomes thing. It's just that this picture looks very similar to the one in my Genetics book so I guess it was Hypomelanosis...
I stand corrected. Chriss and everybody else who answered " Hypomelanosis of Ito " are correct. The underlying cause is Chromosomal Mosaicism and "Hypomelanosis of Ito ", just happens to be one of the examples. So Egyptian doctor is also correct as far as it's underlying cause goes. But becos this is a spot diagnosis - "Hypomelanosis of Ito " seems to be a more appropriate answer. Actually my argument was becos - "Hypomelanosis of Ito " does not respect laterality (unless it is in one of the limbs) and in this image it was just limited to one side in spite of extensive involvement. But I still didn't know what the alternative diagnosis was P: . So I did a image search and found it
ref - U will see the exact image with the diagnosis here - https://www.healthtap.com/#topics/hypopigmented
So if u see this as a genetics question - u may see chromosomal mosaicism in the option and if it's from dermat then .....(-:
ref - Incontinentia pigmenti - Wikipedia, the free encyclopedia & JAMA Network | Archives of Dermatology | The Skin Is Not the Predominant Problem in Incontinentia Pigmenti
Many people in the past were misdiagnosed with a second type of IP, called IP2. This has now been given its own name - 'Hypomelanosis of Ito' (incontinentia pigmenti achromians). This has a slightly different presentation: swirls or streaks of hypopigmentation and depigmentation. It is NOT inherited. It does not inolve skin stages 1 or 2.
ref - wiki
Whorled naevoid hyperpigmentation.
Separate names with a comma.