Inflammaging is a pathological phenomenon and a central concept that brings together an understanding of age-related chronic disease along with functional decline and frailty throughout life. It is a consequence of lifelong exposure of the immune system to antigenic stimuli and complex genetic, environmental, and age-related mechanisms that expose varying degrees of vulnerability or resilience. Dr. Birken recommends the following: Exercise – Reduces inflammatory changes that can lead to a higher risk for age related diseases, such as cardiovascular disease, diabetes, cancer, and Alzheimer’s. Caloric Restriction – Calorie restriction (CR), also known as dietary restriction, has been regarded as the gold standard of many aging interventions to counteract aging. CR together with adequate nutrient intake prolongs maximum lifespan possibly through beneficial metabolic, hormonal, and functional alterations. Hormone Optimization – Since hormones decline as we age, restoration of levels similar to when we were younger can have a profound effect on reducing age-related diseases. Resveratrol – Resveratrol is part of a group of compounds called polyphenols, antioxidants that can protect the body against cellular damage leading to a higher risk for cancer and heart disease. Metformin – Metformin reduces the incidence of aging-related diseases such as neurodegenerative disease and cancer in humans. In spite of its widespread use, the mechanisms by which metformin exerts favorable effects on aging remain largely unknown. Zinc – The anti-aging benefits of a zinc supplement include: cell protection against oxidative stress as well as prevention against aging of the skin Vitamin D – Vitamin D is as crucial for total body function and the muscles as it is for bones. Vitamin D influences hundreds of genes – most cells have vitamin D receptors. Vitamin B Complex – researchers showed that a commercially available form of vitamin B-3, called nicotinamide riboside (NR) chloride — or NIAGEN —boosted a key enzyme in our cells that could potentially slow the aging process Vitamin C – As an antioxidant, it provides protection from free radicals, helps to minimize the appearance of fine lines and wrinkles, brightens and promotes an even skin tone Omega 3 Fish Oil – Research suggests that omega-3 supplements could represent a rare single nutritional intervention that has potential to lower the risk for a host of diseases associated with aging, such as coronary heart disease, Type 2 diabetes, arthritis and Alzheimer’s disease. Probiotic – Oral probiotic supplements are well recognized for protecting the gut’s microflora and supporting the body’s immune system. Healthy bacteria in the gut improve overall health and, consequently, help slow the aging process, enabling skin to retain its youthful glow much longe Arterosil – Contains Rhamnan sulfate a glycocalyx regenerating compound (GRC) and has been reported to possess anticoagulant and antithrombotic activity. CBD – Studies have shown that CBD may help reduce chronic pain by impacting endocannabinoid receptor activity, reducing inflammation and interacting with neurotransmitters Growth Hormone and Growth Hormone Peptides – Growth hormone and peptide therapy can initiate an immediate and significant cascade of positive health results that can directly improve cognition, muscle mass, fat percentage, restful sleep and metabolism. All of which is achieved by potentiating the body’s own innate mechanisms. Dr. Birken recommends daily exercise, proper nutrition, stress reduction (yoga and meditation), hormone optimization including peptide use, and the following supplements: 1. Vitamin D 2. B complex 3. Vitamin C 4. Omega 3 Fish oil 5. Resveratrol 6. Arterosil 7. Zinc 8. Probiotic 9. CBD oil or capsule All of these supplements are available as a pharmaceutical grade in our office. Source
