Binswanger's disease or Subcortical vascular dementia as discribed by Otto Binswanger in 1894 is a form of dementia caused by damage to the white brain matter. Atherosclerosis is the most common cause of Binswanger's disease so it is considered as a particular type of atherosclerosis-related dementia. Binswanger's disease is more common in men between 50 to 70 years old and It is characterized by affection of memory , intellectual function , mood changes and the ability to act or to make decisions. The histologic findings are diffuse, irregular loss of axons and myelin accompanied by gliosis, tissue death. Binswanger's disease has a poor prognosis as there is no cure , also it is considered as one of the most severe types of vascular related dementia , so physicians depends on treating the vascular cause.
good information on Binswanger disease especially After it has been mis diagnosed with other mental diseases
Binswanger disease, also known as subcortical leukoencephalopathy, is a form of small vessel vascular dementia caused by damage to the white brain matter. White matter atrophy can be caused by many circumstances including chronic hypertension as well as old age.This disease is characterized by loss of memory and intellectual function and by changes in mood. These changes encompass what are known as executive functionsof the brain.It usually presents between 54 and 66 years of age, and the first symptoms are usually mental deterioration or stroke.
Binswanger's disease is a kind of dementia caused by a vasculitis of small vessels in the white matter of the brain.