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What's your medical diagnosis...??

Discussion in 'Spot Diagnosis' started by waleed, Sep 25, 2011.

  1. waleed

    waleed Moderator

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    N.B :There is excess oesinophils, NO malignancy
     

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  2. Hendra Gandhi

    Hendra Gandhi Moderator

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    never seen this before, exciting waiting for the right answer :)
     

  3. doctorCiro

    doctorCiro Well-Known Member

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    angiolymphoid hyperplasia with eosinophilia
     

  4. Andrio R

    Andrio R Well-Known Member

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    Measles (rubeola infection)
     

  5. waleed

    waleed Moderator

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    The correct answer is Angiolymphoid hyperplasia with eosinophilia (ALHE) WHich is an uncommon idiopathic condition that manifests in adults as isolated or grouped papules, plaques, or nodules in the skin of the head and neck. Most patients present with lesions in the periauricular region, forehead, or scalp. Rare sites of involvement include the hands, shoulders, breasts, penis, oral mucosa, and orbit.

    A distinct pathologic entity, ALHE is marked by a proliferation of blood vessels with distinctive large endothelial cells. These blood vessels are accompanied by a characteristic inflammatory infiltrate that includes eosinophils. The lesion is benign but may be persistent and is difficult to eradicate. Whether ALHE represents a benign neoplasm or an unusual reaction to varied stimuli, including trauma, remains unclear.
     

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