Discussion in 'Spot Diagnosis' started by waleed, Sep 25, 2011.
N.B :There is excess oesinophils, NO malignancy
never seen this before, exciting waiting for the right answer
angiolymphoid hyperplasia with eosinophilia
Measles (rubeola infection)
The correct answer is Angiolymphoid hyperplasia with eosinophilia (ALHE) WHich is an uncommon idiopathic condition that manifests in adults as isolated or grouped papules, plaques, or nodules in the skin of the head and neck. Most patients present with lesions in the periauricular region, forehead, or scalp. Rare sites of involvement include the hands, shoulders, breasts, penis, oral mucosa, and orbit.
A distinct pathologic entity, ALHE is marked by a proliferation of blood vessels with distinctive large endothelial cells. These blood vessels are accompanied by a characteristic inflammatory infiltrate that includes eosinophils. The lesion is benign but may be persistent and is difficult to eradicate. Whether ALHE represents a benign neoplasm or an unusual reaction to varied stimuli, including trauma, remains unclear.
Separate names with a comma.