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The diagnosis is Athererosclerosis. The picture is of an earlobe crease which is highly suggestive of this diagnosis.
Frank`s sign. A diagonal crease in each earlobe is referred to as Frank’s sign. This sign was originally described as a marker of coronary artery disease, with a moderate sensitivity (approximately 48%) and specificity (approximately 88%). Frank’s sign has been subsequently associated with other cardiovascular risk factors.